Crystal structure of S6K1 kinase domain in complex with a pyrimidine derivative PF-4708671 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole

PDB Details

PDB ID
3WE4
Status
CURRENT
Deposition Date
2013-06-29
Modification Date
2014-10-29
Pubmed ID
25078151
Method
X-RAY DIFFRACTION
Resolution (Å)
2.0
UniProt Accessions
P23443

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DFG 1 18
A C PDIG 2 17
A C DRS 4 6
A C EDI 7 3
A C PDIG 10 2
A N ATP 2 12
A N ATP 5 8
A N DFG 6 6
A N ATP 7 5

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Legend

Color Name Hit Count