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Crystal structure of S6K1 kinase domain in complex with a pyrazolopyrimidine derivative 4-[4-(1H-benzimidazol-2-yl)piperidin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine
PDB Details
PDB ID
3WF5
Status
CURRENT
Deposition Date
2013-07-17
Modification Date
2014-10-29
Pubmed ID
25078151
Method
X-RAY DIFFRACTION
Resolution (Å)
2.1
UniProt Accessions
P23443
Mapping Results
Chain
Terminus
Site
Consensus Site Rank
Consensus Site Population
A
C
DFG
1
15
A
C
PDIG
3
11
A
C
DRS
4
8
A
C
PDIG
7
5
A
C
EDI
10
4
A
N
ATP
0
22
A
N
ATP
6
7
A
N
DFG
8
2
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Chain: A
Legend
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Name
Hit Count
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Chain: A