Crystal Structure of JAK3 Kinase Domain in Complex with a Pyrrolopyrazine-2-phenyl Ether Inhibitor

PDB Details

PDB ID
3ZEP
Status
CURRENT
Deposition Date
2012-12-06
Modification Date
2016-09-14
Pubmed ID
23541670
Method
X-RAY DIFFRACTION
Resolution (Å)
2.35
UniProt Accessions
P52333

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 2 16
A C CMP 10 2
A N DFG 0 20
A N ATP 1 15
A N ATP 2 12
A N ATP 5 5
A N MT3 6 5
A N MPP 13 2

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Legend

Color Name Hit Count