5-aryl-4-carboxamide-1,3-oxazoles: potent and selective GSK-3 inhibitors

PDB Details

PDB ID
4AFJ
Status
CURRENT
Deposition Date
2012-01-19
Modification Date
2012-03-07
Pubmed ID
22310227
Method
X-RAY DIFFRACTION
Resolution (Å)
1.98
UniProt Accessions
P49841

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 1 17
A C DRS 4 4
A C PDIG 5 4
A N ATP 0 19
A N MPP 2 16
A N MT3 4 15
B C EDI 1 16
B C PDIG 5 3
B C DRS 7 3
B C DRS 9 2
B N ATP 4 13
B N MT3 5 12

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Legend

Color Name Hit Count