Discovery of Oral Polo-Like Kinase (PLK) Inhibitors with Enhanced Selectivity Profile using Residue Targeted Drug Design

PDB Details

PDB ID
4B6L
Status
CURRENT
Deposition Date
2012-08-14
Modification Date
2013-08-21
Method
X-RAY DIFFRACTION
Resolution (Å)
1.9
UniProt Accessions
Q9H4B4

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 1 17
A C CMP 2 16
A C EDI 5 8
A N ATP 2 18
A N DFG 4 9
A N DFG 8 3

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Legend

Color Name Hit Count