Structure of L1196M Mutant Human Anaplastic Lymphoma Kinase in Complex with 2-(5-(6-amino-5-((R)-1-(5-fluoro-2-(2H-1,2,3-triazol-2- yl)phenyl)ethoxy)pyridin-3-yl)-4-methylthiazol-2-yl)propane-1,2-diol

PDB Details

PDB ID
4CD0
Status
CURRENT
Deposition Date
2013-10-29
Modification Date
2014-03-12
Pubmed ID
24432909
Method
X-RAY DIFFRACTION
Resolution (Å)
2.23
UniProt Accessions
Q9UM73

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C CMP 0 15
A N PIF 0 19
A N DFG 3 14
A N ATP 5 9

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Legend

Color Name Hit Count