Structure of the Human Anaplastic Lymphoma Kinase in Complex with the inhibitor 2-((1R)-1-((3-amino-6-(2-methoxypyridin-3-yl)pyrazin-2-yl) oxy)ethyl)-4-fluoro-N-methylbenzamide

PDB Details

PDB ID
4CMO
Status
CURRENT
Deposition Date
2014-01-16
Modification Date
2014-06-25
Pubmed ID
24819116
Method
X-RAY DIFFRACTION
Resolution (Å)
2.05
UniProt Accessions
Q9UM73

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C CMP 6 9
A N PIF 0 21
A N ATP 3 11
A N DFG 6 4
A N ATP 7 3
A N MT3 10 2

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Legend

Color Name Hit Count