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Structure of the Human Anaplastic Lymphoma Kinase in Complex with the inhibitor 3-((1R)-1-(5-fluoro-2-(2H-1,2,3-triazol-2-yl)phenyl)ethoxy)- 5-(3-(methylsulfonyl)phenyl)pyridin-2-amine
PDB Details
PDB ID
4CMT
Status
CURRENT
Deposition Date
2014-01-17
Modification Date
2014-06-25
Pubmed ID
24819116
Method
X-RAY DIFFRACTION
Resolution (Å)
1.73
UniProt Accessions
Q9UM73
Mapping Results
Chain
Terminus
Site
Consensus Site Rank
Consensus Site Population
A
C
CMP
0
16
A
C
CMP
5
10
A
N
ATP
5
10
A
N
MPP
6
5
A
N
DFG
7
5
A
N
MT3
8
2
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Chain: A
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Hit Count
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Chain: A