Structure of the Human Anaplastic Lymphoma Kinase in Complex with the inhibitor (10R)-7-amino-12-fluoro-1,3,10,16-tetramethyl-16,17-dihydro- 1H-8,4-(metheno)pyrazolo(4,3-h)(2,5,11)benzoxadiazacyclotetradecin-15(10H)-one

PDB Details

PDB ID
4CMU
Status
CURRENT
Deposition Date
2014-01-17
Modification Date
2014-06-25
Pubmed ID
24819116
Method
X-RAY DIFFRACTION
Resolution (Å)
1.8
UniProt Accessions
Q9UM73

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C CMP 0 15
A N PIF 0 19
A N ATP 4 15
A N DFG 5 4

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Legend

Color Name Hit Count