Structure of the Human Anaplastic Lymphoma Kinase in Complex with the inhibitor (5R)-8-amino-3-fluoro-5,19-dimethyl-20-oxo-5,18,19,20- tetrahydro-7,11-(azeno)pyrido(2',1':2,3)imidazo(4,5-h)(2,5,11) benzoxadiazacyclotetradecine-14-carbonitrile

PDB Details

PDB ID
4CTB
Status
CURRENT
Deposition Date
2014-03-12
Modification Date
2014-06-25
Pubmed ID
24819116
Method
X-RAY DIFFRACTION
Resolution (Å)
1.79
UniProt Accessions
Q9UM73

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C CMP 6 9
A N PIF 1 18
A N ATP 4 8
A N DFG 6 4
A N MT3 8 2

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Legend

Color Name Hit Count