Structure of the Human Anaplastic Lymphoma Kinase in Complex with the inhibitor 7-amino-3-cyclopropyl-12-fluoro-1,10,16-trimethyl-16,17- dihydro-1H-8,4-(metheno)pyrazolo(4,3-h)(2,5,11) benzoxadiazacyclotetradecin-15(10H)-one

PDB Details

PDB ID
4CTC
Status
CURRENT
Deposition Date
2014-03-12
Modification Date
2014-06-25
Pubmed ID
24819116
Method
X-RAY DIFFRACTION
Resolution (Å)
2.03
UniProt Accessions
Q9UM73

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C CMP 0 22
A N DFG 6 8
A N ATP 8 4

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Legend

Color Name Hit Count