Crystal structure of human anaplastic lymphoma kinase in complex with a piperidine-carboxamide inhibitor

PDB Details

PDB ID
4DCE
Status
CURRENT
Deposition Date
2012-01-17
Modification Date
2012-05-09
Pubmed ID
22263917
Method
X-RAY DIFFRACTION
Resolution (Å)
2.03
UniProt Accessions
Q9UM73

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C CMP 2 13
A C DFG 4 12
A C CMP 7 6
A N PIF 0 15
A N DFG 2 12
A N PIF 4 10
A N ATP 6 6
A N MPP 7 5
A N DFG 10 3
B C DFG 2 13
B C CMP 8 6
B N DFG 0 20
B N ATP 5 10
B N MPP 7 2

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Legend

Color Name Hit Count