JAK3 kinase domain in complex with 2-Cyclopropyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid ((S)-2-hydroxy-1,2-dimethyl-propyl)-amide

PDB Details

PDB ID
4HVG
Status
CURRENT
Deposition Date
2012-11-06
Modification Date
2013-01-30
Pubmed ID
23214979
Method
X-RAY DIFFRACTION
Resolution (Å)
2.75
UniProt Accessions
P52333

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 0 22
A C CMP 4 8
A C LBP 5 8
A C AAS 6 5
A C AAS 10 2
A N DFG 3 13
A N ATP 5 8
A N MT3 6 7
A N MPP 7 7

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Legend

Color Name Hit Count