JAK3 kinase domain in complex with 2-Cyclopropyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid ((R)-1-methyl-2-oxo-2-piperidin-1-yl-ethyl)-amide

PDB Details

PDB ID
4HVI
Status
CURRENT
Deposition Date
2012-11-06
Modification Date
2013-01-30
Pubmed ID
23214979
Method
X-RAY DIFFRACTION
Resolution (Å)
2.4
UniProt Accessions
P52333

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 1 16
A C CMP 4 8
A C AAS 5 6
A C LBP 6 5
A C AAS 10 2
A N MT3 0 16
A N ATP 3 11
A N DFG 4 10
A N PIF 5 10
A N MPP 6 8
A N MPP 9 2

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Legend

Color Name Hit Count