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Crystal structure of KIT kinase domain with a small molecule inhibitor, PLX647
PDB Details
PDB ID
4HVS
Status
CURRENT
Deposition Date
2012-11-06
Modification Date
2013-04-17
Pubmed ID
23493555
Method
X-RAY DIFFRACTION
Resolution (Å)
1.9
UniProt Accessions
P10721
Mapping Results
Chain
Terminus
Site
Consensus Site Rank
Consensus Site Population
A
C
CMP
4
8
A
C
DFG
6
7
A
N
MPP
1
15
A
N
MT3
3
13
A
N
DFG
4
12
A
N
ATP
5
9
A
N
MPP
6
6
A
N
ATP
8
2
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Chain: A
Legend
Color
Name
Hit Count
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Chain: A