JAK3 kinase domain in complex with 2-Phenoxy-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid ((S)-1-cyclopropyl-ethyl)-amide

PDB Details

PDB ID
4I6Q
Status
CURRENT
Deposition Date
2012-11-30
Modification Date
2013-10-16
Pubmed ID
23541670
Method
X-RAY DIFFRACTION
Resolution (Å)
1.85
UniProt Accessions
P52333

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C CMP 2 12
A C LBP 4 10
A C PDIG 5 7
A C AAS 6 5
A C AAS 12 2
A N DFG 0 20
A N ATP 2 16
A N PIF 5 9

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Legend

Color Name Hit Count