Crystal structure of Pim1 kinase in complex with inhibitor 2-[(trans-4-aminocyclohexyl)amino]-4-{[3-(trifluoromethyl)phenyl]amino}pyrido[4,3-d]pyrimidin-5(6H)-one

PDB Details

PDB ID
4JX7
Status
CURRENT
Deposition Date
2013-03-27
Modification Date
2013-08-28
Pubmed ID
23936194
Method
X-RAY DIFFRACTION
Resolution (Å)
2.4
UniProt Accessions
P11309

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 1 15
A C CMP 2 14
A C DRS 4 10
A C LBP 10 2
A N ATP 0 21
A N DFG 4 10
A N MT3 5 8
A N ATP 8 2

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Legend

Color Name Hit Count