Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5

PDB Details

PDB ID
4LG4
Status
CURRENT
Deposition Date
2013-06-27
Modification Date
2013-10-30
Pubmed ID
23972470
Method
X-RAY DIFFRACTION
Resolution (Å)
2.42
UniProt Accessions
Q13188

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C AAS 0 21
A C PDIG 2 12
A C AAS 9 2
A N MPP 0 23
A N PIF 1 18
A N DFG 2 16
A N ATP 3 15
A N MT3 5 7
B C PDIG 1 18
B C PDIG 2 16
B C CMP 7 3
B N PIF 0 19
B N MPP 2 16
B N MPP 3 15
B N MT3 4 11
B N DFG 5 7
B N ATP 6 6
C C PDIG 0 23
C C AAS 3 11
C C AAS 4 7
C C CMP 5 7
C N MPP 0 22
C N PIF 1 14
C N ATP 2 13
C N MT3 3 11
C N DFG 4 11
C N ATP 7 4
C N ATP 8 4
D C PDIG 0 18
D C CMP 3 9
D C DRS 6 6
D C AAS 7 6
D C DRS 9 4
D C CMP 10 4
D N MPP 0 20
D N ATP 1 16
D N PIF 2 14
E C PDIG 1 16
E C PDIG 3 11
E N MPP 0 27
E N ATP 1 17
E N PIF 3 15
F C PDIG 0 27
F C AAS 4 9
F C CMP 7 4
F C AAS 8 3
F N PIF 0 23
F N MPP 1 20
F N MPP 2 17
F N MT3 3 14
F N ATP 4 10
F N ATP 6 2
F N DFG 8 2

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Legend

Color Name Hit Count