Discovery of Pyrazolo[1,5a]pyrimidine-based Pim1 Inhibitors

PDB Details

PDB ID
4MBI
Status
CURRENT
Deposition Date
2013-08-19
Modification Date
2013-10-30
Pubmed ID
24091081
Method
X-RAY DIFFRACTION
Resolution (Å)
2.3
UniProt Accessions
P11309

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 1 16
A C CMP 5 9
A C PDIG 6 6
A C LBP 8 4
A C DRS 9 3
A N ATP 2 16
A N DFG 3 11
A N DFG 4 11
A N ATP 5 7
A N ATP 7 2

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Legend

Color Name Hit Count