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Crystal structure of BTK kinase domain complexed with 1-[5-[3-(7-tert-butyl-4-oxo-quinazolin-3-yl)-2-methyl-phenyl]-1-methyl-2-oxo-3-pyridyl]-3-methyl-urea
PDB Details
PDB ID
4OTQ
Status
CURRENT
Deposition Date
2014-02-14
Modification Date
2015-01-21
Pubmed ID
24712864
Method
X-RAY DIFFRACTION
Resolution (Å)
1.55
UniProt Accessions
Q06187
Mapping Results
Chain
Terminus
Site
Consensus Site Rank
Consensus Site Population
A
C
AAS
8
4
A
N
MT3
0
15
A
N
MT3
2
15
A
N
ATP
3
13
A
N
MPP
4
11
A
N
MT3
6
8
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Chain: A
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Name
Hit Count
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Chain: A