The structure of TrkA kinase bound to the inhibitor N-(3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)-2-{4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl}acetamide

PDB Details

PDB ID
4PMM
Status
CURRENT
Deposition Date
2014-05-22
Modification Date
2015-02-25
Pubmed ID
24914455
Method
X-RAY DIFFRACTION
Resolution (Å)
2.0
UniProt Accessions
P04629

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 0 25
A C DFG 1 21
A C ATP 2 16
A C DRS 4 6
A C PDIG 5 5
A C DRS 7 3
A C PDIG 8 3
A N ATP 0 20
A N MPP 1 18
A N ATP 6 4
A N DFG 7 4

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Legend

Color Name Hit Count