The structure of TrkA kinase bound to the inhibitor 4-naphthalen-1-yl-1-[(5-phenyl-1,2,4-oxadiazol-3-yl)methyl]-1H-pyrrolo[3,2-c]pyridine-2-carboxylic acid

PDB Details

PDB ID
4PMS
Status
CURRENT
Deposition Date
2014-05-22
Modification Date
2015-02-25
Pubmed ID
24914455
Method
X-RAY DIFFRACTION
Resolution (Å)
2.8
UniProt Accessions
P04629

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 0 22
A C DFG 1 21
A C PDIG 3 13
A C DRS 4 7
A C DRS 6 5
A C ATP 7 2
A N ATP 0 18
A N MPP 3 14
A N MT3 4 14
A N ATP 6 6

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Legend

Color Name Hit Count