Crystal Structure of FGF Receptor (FGFR) 4 Kinase Domain in Complex with FIIN-2, an Irreversible Tyrosine Kinase Inhibitor Capable of Overcoming FGFR Kinase Gate-Keeper Mutations

PDB Details

PDB ID
4QQC
Status
CURRENT
Deposition Date
2014-06-27
Modification Date
2014-11-26
Pubmed ID
25349422
Method
X-RAY DIFFRACTION
Resolution (Å)
2.4
UniProt Accessions
P22455

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DFG 3 13
A N MT3 1 14
A N MPP 3 13
A N DFG 5 7
A N ATP 6 5

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Legend

Color Name Hit Count