Crystal Structure of the Tyrosine Kinase Domain of FGF Receptor 4 in Complex with Ponatinib

PDB Details

PDB ID
4QRC
Status
CURRENT
Deposition Date
2014-06-30
Modification Date
2015-01-28
Pubmed ID
25317566
Method
X-RAY DIFFRACTION
Resolution (Å)
1.9
UniProt Accessions
P22455

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C CMP 0 24
A C DFG 4 7
A C DEF 6 5
A C DFG 7 3
A N MPP 0 21
A N ATP 1 18
A N DFG 3 12
A N MPP 4 11
A N ATP 6 7

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Legend

Color Name Hit Count