JAK3 kinase domain in complex with 1-[(3S)-1-isobutylsulfonyl-3-piperidyl]-3-(5H-pyrrolo[2,3-b]pyrazin-2-yl)urea

PDB Details

PDB ID
4QT1
Status
CURRENT
Deposition Date
2014-07-07
Modification Date
2015-05-27
Pubmed ID
25262541
Method
X-RAY DIFFRACTION
Resolution (Å)
2.4
UniProt Accessions
P52333

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 0 18
A C CMP 5 7
A C LBP 6 5
A C AAS 8 3
A C AAS 10 2
A N MPP 1 18
A N DFG 2 18
A N ATP 5 4

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Legend

Color Name Hit Count