Crystal structure of BTK kinase domain complexed with 6-(dimethylamino)-2-[2-(hydroxymethyl)-3-[1-methyl-5-[[5-(morpholine-4-carbonyl)-2-pyridyl]amino]-6-oxo-3-pyridyl]phenyl]-3,4-dihydroisoquinolin-1-one

PDB Details

PDB ID
4RFY
Status
CURRENT
Deposition Date
2014-09-29
Modification Date
2015-01-14
Pubmed ID
25466710
Method
X-RAY DIFFRACTION
Resolution (Å)
1.7
UniProt Accessions
Q06187

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C AAS 8 5
A N MT3 0 38
A N ATP 2 13
A N MPP 3 11
A N MT3 4 4
A N ATP 7 2
A N MPP 8 2
A N ATP 9 2

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Legend

Color Name Hit Count