Crystal structure of BTK kinase domain complexed with 2-[8-fluoro-2-[2-(hydroxymethyl)-3-[1-methyl-5-[[5-(4-methylpiperazin-1-yl)-2-pyridyl]amino]-6-oxo-3-pyridyl]phenyl]-1-oxo-3,4-dihydroisoquinolin-6-yl]-2-methyl-propanenitrile

PDB Details

PDB ID
4RG0
Status
CURRENT
Deposition Date
2014-09-29
Modification Date
2015-01-14
Pubmed ID
25466710
Method
X-RAY DIFFRACTION
Resolution (Å)
2.5
UniProt Accessions
Q06187

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C AAS 7 5
A N MT3 2 13
A N ATP 3 13
A N MT3 4 13
A N MPP 5 11
A N MPP 9 2

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Legend

Color Name Hit Count