The crystal structure of human abl1 T315I gatekeeper mutant kinase domain in complex with axitinib

PDB Details

PDB ID
4TWP
Status
CURRENT
Deposition Date
2014-07-01
Modification Date
2015-05-13
Pubmed ID
25686603
Method
X-RAY DIFFRACTION
Resolution (Å)
2.4
UniProt Accessions
P00519

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C CMP 2 12
A C DRS 6 6
A C DEF 7 5
A C CMP 8 4
A C PDIG 11 2
A N ATP 0 28
A N MPP 1 17
A N MPP 2 15
A N ATP 4 9
A N DFG 7 3

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Legend

Color Name Hit Count