SAR156497 an exquisitely selective inhibitor of Aurora kinases

PDB Details

PDB ID
4UYN
Status
CURRENT
Deposition Date
2014-09-02
Modification Date
2015-01-21
Pubmed ID
25369539
Method
X-RAY DIFFRACTION
Resolution (Å)
1.9
UniProt Accessions
O14965

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 2 15
A C AAS 3 10
A C DRS 6 5
A C AAS 7 5
A N ATP 0 21
A N MPP 1 18
A N MT3 2 16
A N PIF 7 3
A N ATP 8 2

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Legend

Color Name Hit Count