Crystal structure of human Pim-1 kinase in complex with an azaspiro pyrazinyl-indazole inhibitor.

PDB Details

PDB ID
4WRS
Status
CURRENT
Deposition Date
2014-10-25
Modification Date
2015-02-11
Pubmed ID
25597005
Method
X-RAY DIFFRACTION
Resolution (Å)
2.2
UniProt Accessions
P11309

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 1 16
A C PDIG 2 16
A C DRS 3 10
A C CMP 5 8
A C DRS 6 5
A C PDIG 7 4
A C LBP 9 2
A N MT3 0 28
A N DFG 2 15
A N ATP 3 14
A N ATP 5 6
A N ATP 6 4

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Legend

Color Name Hit Count