Crystal structure of human Pim-1 kinase in complex with a thiazolamine-indazole inhibitor.

PDB Details

PDB ID
4WSY
Status
CURRENT
Deposition Date
2014-10-28
Modification Date
2015-02-11
Pubmed ID
25616902
Method
X-RAY DIFFRACTION
Resolution (Å)
2.3
UniProt Accessions
P11309

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 1 16
A C PDIG 2 15
A C DRS 3 12
A C CMP 4 11
A C PDIG 6 8
A C DRS 7 4
A N ATP 1 18
A N DFG 4 14
A N ATP 5 5
A N MT3 6 3
A N ATP 7 2

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Legend

Color Name Hit Count