Crystal structure of human Pim-1 kinase in complex with a thiadiazolamine-indole inhibitor.

PDB Details

PDB ID
4WT6
Status
CURRENT
Deposition Date
2014-10-29
Modification Date
2015-02-11
Pubmed ID
25616902
Method
X-RAY DIFFRACTION
Resolution (Å)
2.3
UniProt Accessions
P11309

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 1 16
A C DRS 2 15
A C PDIG 3 14
A C DRS 5 6
A C PDIG 6 4
A C LBP 7 3
A C DRS 8 3
A N MT3 0 23
A N ATP 1 19
A N DFG 4 11
A N ATP 7 4

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Legend

Color Name Hit Count