Discovery of VX-509 (Decernotinib): A Potent and Selective Janus kinase (JAK) 3 Inhibitor for the Treatment of Autoimmune Diseases

PDB Details

PDB ID
4YTF
Status
CURRENT
Deposition Date
2015-03-17
Modification Date
2015-10-07
Pubmed ID
26230873
Method
X-RAY DIFFRACTION
Resolution (Å)
1.78
UniProt Accessions
O60674

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DEF 4 13
A C PDIG 5 11
A C PDIG 7 3
A N ATP 1 16
A N DFG 2 15
A N MT3 6 3
A N ATP 8 2

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Legend

Color Name Hit Count