Discovery of VX-509 (Decernotinib): A Potent and Selective Janus kinase (JAK) 3 Inhibitor for the Treatment of Autoimmune Diseases

PDB Details

PDB ID
4YTH
Status
CURRENT
Deposition Date
2015-03-17
Modification Date
2016-07-20
Pubmed ID
26230873
Method
X-RAY DIFFRACTION
Resolution (Å)
2.04
UniProt Accessions
O60674

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DEF 4 12
A C PDIG 5 9
A C PDIG 8 2
A N ATP 0 17
A N DFG 1 16
A N MPP 3 14
A N ATP 6 6
A N ATP 9 2

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Legend

Color Name Hit Count