Discovery of VX-509 (Decernotinib): A Potent and Selective Janus kinase (JAK) 3 Inhibitor for the Treatment of Autoimmune Disease

PDB Details

PDB ID
4YTI
Status
CURRENT
Deposition Date
2015-03-17
Modification Date
2015-10-07
Pubmed ID
26230873
Method
X-RAY DIFFRACTION
Resolution (Å)
2.52
UniProt Accessions
O60674

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DEF 2 16
A C PDIG 5 12
A C PDIG 7 3
A N DFG 0 19
A N ATP 1 18
A N MPP 3 9
A N ATP 7 4

Mapping Results Viewer

Use your mouse to drag, rotate, and zoom. Select structure to view on the right using dropdown.
Powered by NGL

Legend

Color Name Hit Count