Discovery of 3,5-substituted 6-azaindazoles as potent pan-Pim inhibitors

PDB Details

PDB ID
5DGZ
Status
CURRENT
Deposition Date
2015-08-29
Modification Date
2015-11-11
Pubmed ID
26459208
Method
X-RAY DIFFRACTION
Resolution (Å)
2.5
UniProt Accessions
P11309

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 0 18
A C EDI 1 17
A C DRS 3 12
A C PDIG 4 8
A C CMP 5 8
A C DRS 6 6
A C LBP 8 4
A N ATP 1 19
A N DFG 3 11
A N ATP 8 2

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Legend

Color Name Hit Count