Crystal structure of human Pim-1 kinase in complex with a macrocyclic quinoxaline-pyrrolodihydropiperidinone inhibitor

PDB Details

PDB ID
5EOL
Status
CURRENT
Deposition Date
2015-11-10
Modification Date
2016-05-04
Pubmed ID
27096050
Method
X-RAY DIFFRACTION
Resolution (Å)
2.2
UniProt Accessions
P11309

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 1 17
A C DRS 3 12
A C CMP 5 7
A C DRS 6 7
A C PDIG 7 4
A N ATP 1 17
A N DFG 3 14
A N MT3 4 10
A N ATP 5 8

Mapping Results Viewer

Use your mouse to drag, rotate, and zoom. Select structure to view on the right using dropdown.

Legend

Color Name Hit Count