Dissecting Therapeutic Resistance to ERK Inhibition Rat Wild Type SCH772984 in complex with (3R)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-N-[3-(pyridin-4-yl)-2H-indazol-5-yl]pyrrolidine-3-carboxamide

PDB Details

PDB ID
5HD4
Status
CURRENT
Deposition Date
2016-01-04
Modification Date
2016-06-01
Pubmed ID
26832798
Method
X-RAY DIFFRACTION
Resolution (Å)
1.45
UniProt Accessions
P63086

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 0 16
A C EDI 5 10
A N MT3 0 20
A N PIF 1 17
A N ATP 3 11
A N PIF 5 8

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Legend

Color Name Hit Count