Crystal structure of insulin receptor kinase domain in complex with cis-(R)-7-(3-(azetidin-1-ylmethyl)cyclobutyl)-5-(3-((tetrahydro-2H-pyran-2-yl)methoxy)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine.

PDB Details

PDB ID
5HHW
Status
CURRENT
Deposition Date
2016-01-11
Modification Date
2016-04-13
Pubmed ID
26951750
Method
X-RAY DIFFRACTION
Resolution (Å)
1.79
UniProt Accessions
P06213

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C CMP 1 24
A N MPP 0 27
A N MT3 2 17
A N ATP 3 10
A N ATP 5 5
A N DFG 6 4
A N MPP 7 3
A N MT3 9 1

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Legend

Color Name Hit Count