Design, synthesis and structure activity relationship of potent pan-PIM kinase inhibitors derived from the pyridyl-amide scaffold

PDB Details

PDB ID
5IIS
Status
CURRENT
Deposition Date
2016-03-01
Modification Date
2016-05-04
Pubmed ID
26995528
Method
X-RAY DIFFRACTION
Resolution (Å)
2.1
UniProt Accessions
P11309

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 0 17
A C DRS 5 11
A C DRS 6 4
A C CMP 8 3
A C PDIG 9 3
A N MT3 0 22
A N ATP 1 19
A N DFG 3 10
A N ATP 4 10

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Legend

Color Name Hit Count