O00311

Background

Protein Name
Cell division cycle 7-related protein kinase
Gene Name
CDC7
Organism
Homo sapiens

Annotations

Function
Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylates MCM2 and MCM3.

Mapping Statistics

Site Maximum Consensus Site Population Minimum Consensus Site Population Median Consensus Site Population
EDI 17 2 7.0
MT3 7 2 2.0
PIF 21 3 13.0
ATP 9 4 5.5
MPP 22 16 16.0

Mapping Results

PDB ID Maximum Consensus Site Population
EDI site MT3 site PIF site ATP site DEF site DRS site AAS site MPP site DFG site LBP site CMP site PDIG site PMP site
Total Druggable Structures per Site 3 0 2 0 0 0 0 4 0 0 0 0 0
4F9A 16 2 16 9 0 0 0 17 0 0 0 0 0
4F9C 12 7 13 5 0 0 0 16 0 0 0 0 0
AFO00311 0 0 0 0 0 0 0 0 0 0 0 0 0
4F99 16 2 21 6 0 0 0 22 0 0 0 0 0
4F9B 17 4 15 5 0 0 0 16 0 0 0 0 0