- Protein Name
- Cell division cycle 7-related protein kinase
- Gene Name
- CDC7
- Organism
-
Homo sapiens
- Function
- Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylates MCM2 and MCM3.
| Site |
Maximum Consensus Site Population |
Minimum Consensus Site Population |
Median Consensus Site Population |
| MPP |
22 |
16 |
16.0 |
| PIF |
21 |
3 |
13.0 |
| EDI |
17 |
2 |
7.0 |
| MT3 |
7 |
2 |
2.0 |
| ATP |
9 |
4 |
5.5 |
| PDB ID |
Maximum Consensus Site Population |
| MPP site |
DFG site |
PIF site |
DRS site |
DEF site |
EDI site |
MT3 site |
AAS site |
LBP site |
CMP site |
PDIG site |
ATP site |
PMP site |
| Total Druggable Structures per Site |
4 |
0 |
2 |
0 |
0 |
3 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
|
4F9C
|
16 |
0 |
13 |
0 |
0 |
12 |
7 |
0 |
0 |
0 |
0 |
5 |
0 |
|
4F9A
|
17 |
0 |
16 |
0 |
0 |
16 |
2 |
0 |
0 |
0 |
0 |
9 |
0 |
|
AFO00311
|
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
|
4F99
|
22 |
0 |
21 |
0 |
0 |
16 |
2 |
0 |
0 |
0 |
0 |
6 |
0 |
|
4F9B
|
16 |
0 |
15 |
0 |
0 |
17 |
4 |
0 |
0 |
0 |
0 |
5 |
0 |