O00506

Background

Protein Name
Serine/threonine-protein kinase 25
Gene Name
STK25
Organism
Homo sapiens

Annotations

Function
Oxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets to the Golgi apparatus where it appears to regulate protein transport events, cell adhesion, and polarity complexes important for cell migration.

Mapping Statistics

Site Maximum Consensus Site Population Minimum Consensus Site Population Median Consensus Site Population
MPP 17 5 14.0
DFG 4 4 4.0
PIF 17 9 13.0
DRS 17 4 5.0
CMP 2 2 2.0
PDIG 13 5 9.0
ATP 19 4 4.0

Mapping Results

PDB ID Maximum Consensus Site Population
MPP site DFG site PIF site DRS site DEF site EDI site MT3 site AAS site LBP site CMP site PDIG site ATP site PMP site
Total Druggable Structures per Site 1 0 1 1 0 0 0 0 0 0 0 1 0
4NZW 14 0 14 0 0 0 0 0 0 0 13 19 0
2XIK 17 4 17 17 0 0 0 0 0 2 9 0 0