O00506

Background

Protein Name
Serine/threonine-protein kinase 25
Gene Name
STK25
Organism
Homo sapiens

Annotations

Function
Oxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets to the Golgi apparatus where it appears to regulate protein transport events, cell adhesion, and polarity complexes important for cell migration.

Mapping Statistics

Site Maximum Consensus Site Population Minimum Consensus Site Population Median Consensus Site Population
MPP 17 5 14.0
ATP 19 4 4.0
DFG 4 4 4.0
CMP 2 2 2.0
DRS 17 4 5.0
PDIG 13 5 9.0
PIF 17 9 13.0

Mapping Results

PDB ID Maximum Consensus Site Population
MPP site AAS site MT3 site LBP site ATP site DEF site DFG site CMP site PMP site EDI site DRS site PDIG site PIF site
Total Druggable Structures per Site 1 0 0 0 1 0 0 0 0 0 1 0 1
2XIK 17 0 0 0 0 0 4 2 0 0 17 9 17
4NZW 14 0 0 0 19 0 0 0 0 0 0 13 14