- Protein Name
- Phosphorylase b kinase gamma catalytic chain, liver/testis isoform
- Gene Name
- PHKG2
- Organism
-
Homo sapiens
- Function
- Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. May regulate glycogeneolysis in the testis. In vitro, phosphorylates PYGM (By similarity).
| Site |
Maximum Consensus Site Population |
Minimum Consensus Site Population |
Median Consensus Site Population |
| PIF |
14 |
8 |
10.0 |
| EDI |
2 |
2 |
2.0 |
| AAS |
14 |
3 |
5.0 |
| CMP |
24 |
3 |
19.0 |
| PDIG |
17 |
11 |
13.0 |
| ATP |
18 |
11 |
13.5 |
| PDB ID |
Maximum Consensus Site Population |
| MPP site |
DFG site |
PIF site |
DRS site |
DEF site |
EDI site |
MT3 site |
AAS site |
LBP site |
CMP site |
PDIG site |
ATP site |
PMP site |
| Total Druggable Structures per Site |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
1 |
1 |
1 |
0 |
|
2Y7J
|
0 |
0 |
14 |
0 |
0 |
2 |
0 |
14 |
0 |
24 |
14 |
18 |
0 |
|
AFP15735
|
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
17 |
0 |
0 |