- Protein Name
- Phosphorylase b kinase gamma catalytic chain, liver/testis isoform
- Gene Name
- PHKG2
- Organism
-
Homo sapiens
- Function
- Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. May regulate glycogeneolysis in the testis. In vitro, phosphorylates PYGM (By similarity).
| Site |
Maximum Consensus Site Population |
Minimum Consensus Site Population |
Median Consensus Site Population |
| AAS |
14 |
3 |
5.0 |
| ATP |
18 |
11 |
13.5 |
| CMP |
24 |
3 |
19.0 |
| EDI |
2 |
2 |
2.0 |
| PDIG |
17 |
11 |
13.0 |
| PIF |
14 |
8 |
10.0 |
| PDB ID |
Maximum Consensus Site Population |
| MPP site |
AAS site |
MT3 site |
LBP site |
ATP site |
DEF site |
DFG site |
CMP site |
PMP site |
EDI site |
DRS site |
PDIG site |
PIF site |
| Total Druggable Structures per Site |
0 |
0 |
0 |
0 |
1 |
0 |
0 |
1 |
0 |
0 |
0 |
1 |
0 |
|
AFP15735
|
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
17 |
0 |
|
2Y7J
|
0 |
14 |
0 |
0 |
18 |
0 |
0 |
24 |
0 |
2 |
0 |
14 |
14 |