- Function
- Regulator of muscle contraction and relaxation. Senses mechanical strain that occurs during muscle activity by unfolding in clearly resolvable steps at differing forces.
| Site |
Maximum Consensus Site Population |
Minimum Consensus Site Population |
Median Consensus Site Population |
| MPP |
12 |
6 |
9.0 |
| DFG |
3 |
3 |
3.0 |
| EDI |
8 |
8 |
8.0 |
| MT3 |
14 |
14 |
14.0 |
| AAS |
16 |
1 |
6.0 |
| ATP |
18 |
12 |
15.0 |
| PDB ID |
Maximum Consensus Site Population |
| MPP site |
DFG site |
PIF site |
DRS site |
DEF site |
EDI site |
MT3 site |
AAS site |
LBP site |
CMP site |
PDIG site |
ATP site |
PMP site |
| Total Druggable Structures per Site |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
1 |
0 |
0 |
0 |
1 |
0 |
|
3UTO
|
6 |
3 |
0 |
0 |
0 |
8 |
0 |
16 |
0 |
0 |
0 |
12 |
0 |
|
1KOA
|
12 |
0 |
0 |
0 |
0 |
0 |
14 |
6 |
0 |
0 |
0 |
18 |
0 |