- Protein Name
- Tribbles homolog 1
- Gene Name
- TRIB1
- Organism
-
Homo sapiens
- Function
- Interacts with MAPK kinases and regulates activation of MAP kinases. May not display kinase activity.
| Site |
Maximum Consensus Site Population |
Minimum Consensus Site Population |
Median Consensus Site Population |
| MPP |
12 |
12 |
12.0 |
| EDI |
17 |
12 |
14.5 |
| MT3 |
44 |
8 |
26.0 |
| AAS |
29 |
2 |
19.0 |
| CMP |
16 |
16 |
16.0 |
| PDIG |
17 |
17 |
17.0 |
| ATP |
23 |
23 |
23.0 |
| PDB ID |
Maximum Consensus Site Population |
| MPP site |
DFG site |
PIF site |
DRS site |
DEF site |
EDI site |
MT3 site |
AAS site |
LBP site |
CMP site |
PDIG site |
ATP site |
PMP site |
| Total Druggable Structures per Site |
0 |
0 |
0 |
0 |
0 |
1 |
1 |
2 |
0 |
1 |
1 |
1 |
0 |
|
5CEK
|
12 |
0 |
0 |
0 |
0 |
17 |
44 |
29 |
0 |
0 |
0 |
0 |
0 |
|
5CEM
|
0 |
0 |
0 |
0 |
0 |
12 |
8 |
24 |
0 |
16 |
0 |
23 |
0 |
|
AFQ96RU8
|
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
17 |
0 |
0 |