- Protein Name
- STE20-like serine/threonine-protein kinase
- Gene Name
- SLK
- Organism
-
Homo sapiens
- Function
- Mediates apoptosis and actin stress fiber dissolution.
| Site |
Maximum Consensus Site Population |
Minimum Consensus Site Population |
Median Consensus Site Population |
| MPP |
20 |
16 |
16.0 |
| DFG |
4 |
1 |
2.5 |
| DRS |
3 |
3 |
3.0 |
| MT3 |
16 |
4 |
12.0 |
| AAS |
22 |
2 |
16.0 |
| CMP |
19 |
19 |
19.0 |
| PDIG |
14 |
14 |
14.0 |
| ATP |
17 |
2 |
6.0 |
| PDB ID |
Maximum Consensus Site Population |
| MPP site |
DFG site |
PIF site |
DRS site |
DEF site |
EDI site |
MT3 site |
AAS site |
LBP site |
CMP site |
PDIG site |
ATP site |
PMP site |
| Total Druggable Structures per Site |
5 |
0 |
0 |
0 |
0 |
0 |
1 |
5 |
0 |
1 |
0 |
1 |
0 |
|
2JFL
|
18 |
0 |
0 |
0 |
0 |
0 |
0 |
18 |
0 |
0 |
0 |
8 |
0 |
|
2J51
|
16 |
0 |
0 |
0 |
0 |
0 |
0 |
20 |
0 |
0 |
0 |
7 |
0 |
|
2JFM
|
16 |
4 |
0 |
0 |
0 |
0 |
12 |
20 |
0 |
0 |
0 |
5 |
0 |
|
2UV2
|
20 |
1 |
0 |
0 |
0 |
0 |
4 |
18 |
0 |
0 |
0 |
9 |
0 |
|
AFQ9H2G2
|
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
14 |
0 |
0 |
|
4USF
|
16 |
0 |
0 |
3 |
0 |
0 |
16 |
22 |
0 |
19 |
0 |
17 |
0 |