- Protein Name
- Casein kinase I isoform gamma-1
- Gene Name
- CSNK1G1
- Organism
-
Homo sapiens
- Function
- Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate (By similarity). Phosphorylates CLSPN.
| Site |
Maximum Consensus Site Population |
Minimum Consensus Site Population |
Median Consensus Site Population |
| MPP |
22 |
22 |
22.0 |
| DFG |
3 |
3 |
3.0 |
| DRS |
14 |
14 |
14.0 |
| EDI |
4 |
4 |
4.0 |
| AAS |
20 |
2 |
11.0 |
| CMP |
19 |
19 |
19.0 |
| ATP |
23 |
23 |
23.0 |
| PDB ID |
Maximum Consensus Site Population |
| MPP site |
DFG site |
PIF site |
DRS site |
DEF site |
EDI site |
MT3 site |
AAS site |
LBP site |
CMP site |
PDIG site |
ATP site |
PMP site |
| Total Druggable Structures per Site |
1 |
0 |
0 |
0 |
0 |
0 |
0 |
1 |
0 |
1 |
0 |
1 |
0 |
|
2CMW
|
22 |
3 |
0 |
14 |
0 |
4 |
0 |
20 |
0 |
19 |
0 |
23 |
0 |