- Protein Name
- Inactive LRR receptor-like serine/threonine-protein kinase BIR2
- Gene Name
- BIR2
- Organism
-
Arabidopsis thaliana
- Function
- Pseudokinases lacking protein kinase activity and unable to bind ATP-analogs (PubMed:24556575). Negative regulator of pathogen-associated molecular patterns- (PAMP-) triggered immunity by limiting BAK1-receptor complex formation in the absence of ligands (PubMed:24388849).
| Site |
Maximum Consensus Site Population |
Minimum Consensus Site Population |
Median Consensus Site Population |
| MPP |
23 |
23 |
23.0 |
| DRS |
15 |
5 |
9.5 |
| MT3 |
4 |
4 |
4.0 |
| AAS |
3 |
3 |
3.0 |
| ATP |
9 |
4 |
6.5 |
| PDB ID |
Maximum Consensus Site Population |
| MPP site |
DFG site |
PIF site |
DRS site |
DEF site |
EDI site |
MT3 site |
AAS site |
LBP site |
CMP site |
PDIG site |
ATP site |
PMP site |
| Total Druggable Structures per Site |
1 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
|
4L68
|
23 |
0 |
0 |
15 |
0 |
0 |
4 |
3 |
0 |
0 |
0 |
9 |
0 |