- Protein Name
- Casein kinase I isoform gamma-3
- Gene Name
- CSNK1G3
- Organism
-
Homo sapiens
- Function
- Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate (By similarity).
| Site |
Maximum Consensus Site Population |
Minimum Consensus Site Population |
Median Consensus Site Population |
| MPP |
7 |
3 |
4.0 |
| DFG |
13 |
2 |
13.0 |
| PIF |
16 |
3 |
5.0 |
| DRS |
31 |
1 |
13.0 |
| EDI |
12 |
2 |
6.0 |
| MT3 |
9 |
3 |
6.0 |
| AAS |
18 |
2 |
3.5 |
| LBP |
2 |
2 |
2.0 |
| CMP |
14 |
2 |
8.5 |
| ATP |
26 |
5 |
14.5 |
| PDB ID |
Maximum Consensus Site Population |
| MPP site |
DFG site |
PIF site |
DRS site |
DEF site |
EDI site |
MT3 site |
AAS site |
LBP site |
CMP site |
PDIG site |
ATP site |
PMP site |
| Total Druggable Structures per Site |
0 |
0 |
1 |
5 |
0 |
0 |
0 |
1 |
0 |
0 |
0 |
3 |
0 |
|
4G16
|
0 |
0 |
16 |
28 |
0 |
7 |
0 |
18 |
0 |
0 |
0 |
0 |
0 |
|
2IZR
|
3 |
2 |
0 |
10 |
0 |
3 |
0 |
0 |
0 |
8 |
0 |
13 |
0 |
|
2CHL
|
0 |
0 |
0 |
31 |
0 |
6 |
0 |
0 |
2 |
0 |
0 |
0 |
0 |
|
4HGL
|
0 |
0 |
10 |
25 |
0 |
5 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
|
2IZU
|
5 |
13 |
0 |
15 |
0 |
12 |
9 |
0 |
0 |
14 |
0 |
25 |
0 |
|
2IZS
|
7 |
0 |
0 |
15 |
0 |
2 |
3 |
0 |
0 |
2 |
0 |
16 |
0 |
|
2IZT
|
4 |
13 |
0 |
13 |
0 |
5 |
0 |
0 |
0 |
9 |
0 |
26 |
0 |
|
4G17
|
0 |
0 |
5 |
26 |
0 |
6 |
0 |
2 |
0 |
0 |
0 |
0 |
0 |
|
4HGS
|
0 |
0 |
5 |
27 |
0 |
7 |
0 |
2 |
0 |
0 |
0 |
0 |
0 |