- Protein Name
- STE20/SPS1-related proline-alanine-rich protein kinase
- Gene Name
- Stk39
- Organism
-
Mus musculus
- Function
- May act as a mediator of stress-activated signals. Mediates the inhibiton of SLC4A4, SLC26A6 as well as CFTR activities by the WNK scaffolds, probably through phosphorylation (PubMed:21317537, PubMed:23542070).
| Site |
Maximum Consensus Site Population |
Minimum Consensus Site Population |
Median Consensus Site Population |
| PIF |
18 |
18 |
18.0 |
| DRS |
5 |
3 |
3.0 |
| MT3 |
19 |
1 |
4.0 |
| AAS |
22 |
2 |
15.0 |
| ATP |
16 |
8 |
12.0 |
| PDB ID |
Maximum Consensus Site Population |
| MPP site |
DFG site |
PIF site |
DRS site |
DEF site |
EDI site |
MT3 site |
AAS site |
LBP site |
CMP site |
PDIG site |
ATP site |
PMP site |
| Total Druggable Structures per Site |
0 |
0 |
1 |
0 |
0 |
0 |
1 |
2 |
0 |
0 |
0 |
1 |
0 |
|
5DBX
|
0 |
0 |
0 |
5 |
0 |
0 |
6 |
17 |
0 |
0 |
0 |
16 |
0 |
|
AFQ9Z1W9
|
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
|
5D9H
|
0 |
0 |
18 |
3 |
0 |
0 |
19 |
22 |
0 |
0 |
0 |
8 |
0 |